Survey Protocols


Well-designed and executed surveys define the beginning of the rational development effort. 

Far from trial-and-error, the survey of options within a unit operation is delineated by the nature of the matrix, the structure and stability of the compound, and the scope of the project.  We will show you how to choose surveys that will reveal the behaviour of the target molecule in its matrix. 

API Purifications consultants can show you how to develop time-efficient protocols for every major unit operation:

Extraction
Lysis
Centrifugation
Membrane Filtration
Depth Filtration
Pressing

Liquid/Liquid Extraction
Solid Phase Extraction

Flash Chromatography
Low Pressure Liquid Chromatography
High Pressure Liquid Chromatography
Preparative HPLC
Preparative TLC

Crystallization
Precipitation

Drying
Lyophilization

We can also show you how to develop rational approaches to sample preparation, routine analytical HPLC method development, and routine scaling from analytical HPLC to preparative HPLC.